Organized by the Faculty of Medicine and Lille University Hospital.
Under the auspices of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC), The Société Française de lute contre les Cancers et les leucémies de l’Enfant et de l’adolescent (SFCE), The société Française d’Immunologie (SFI), The club d’ImmunoThérapie Cellulaire (CITC)The Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL), The Intergroup Francophone du Myélome (IFM), and The Lymphoma Study Association (LYSA).
You can download the latest version of the program here
Wednesday September 6th, 2023
08:00 – Welcome and registration
09:45 – Introduction
Frédéric Boiron, General Director of Lille University Hospital TBC
Ibrahim Yakoub-Agha and Suman Mitra
Engineering the next-generation of CAR T-cells
Chairs: Ignacio Moraga (Dundee; Scotland) & chair(s) (city, country)
10:00 – Fighting fire with fire: Boosting T cell-based immunotherapies by mitochondrial transfer
Luca Gattinoni (Regensburg, Germany)
10:25 – Neoantigen Reactive TILs: Key to Next-gen Cell Therapies
Sri Krishna (Bethesda, USA)
10:50 – Exploring Cell-Specific Viral Entry Approaches to improve gene and cellular immunotherapy
Els Verhoeyen (Nice, FRANCE)
11:15 – Methods to edit T cells for cancer immunotherapy
Laurie Menger (Paris, France) TBC
11:40 – Biomarkers to inform CAR-T therapies
Joseph Melenhorst (Cleveland, USA)
12:00 – Coffee break
12:30 – 13:15
Keynote lecture
Chair(s): name(s) of chair(s) (city, country)
Marcela Maus (USA)
13:15 – Lunch break
Industrial Symposium I
Chair(s): name(s) of chair(s) (city, country)
14:00 – Title
Name of presenter (city, country)
14:30 – Title
Name of presenter (city, country)
Industrial Symposium II
Chair(s): name(s) of chair(s) (city, coutry)
15:00 – Title
Name of presenter (city, country)
15:30 – Title
Name of presenter (city, country)
16:00 – Coffee break
16:30
Special lecture : Pioneering the In Vivo Cell Engineering Approaches for cancer treatments
Chairs : Suman Mitra (Lille, France) & Ibrahim Yakoub-Agha (Lille, France)
Gill SAAR (Philadelphia, USA)
Session LYSA
Chair(s) :Franck Morschhauser (Lille, France) & Noël Milpied (Bordeaux, France)
17:00 – Blood transfusion in CAR T-cell therapy for lymphomas
Samuel vic (Rennes, France)
17:20 – ALYCANTE: CtDNA and PET scan
Marie-Hélène Delfau (Créteil, France)
17:40 – Title
Name of presenter (city, coutry)
18:00 – Closing remarks
Thursday September 7th, 2023
08:30 – Welcome and registration
Session IFM
Chairs : Thierry Facon (Lille, France) & Philippe Moreau (Nantes, France)
09:00 – CAR T cells in MM from clinical studies to real life: Where are we ?
Xavier Leleu (Poitiers, France)
09:20 – Relapse after anti BCMA CAR T cells: Outcome and mechanisms of resistance
Bertrand Arnulf (Paris, France)
09:40 – Future directions for cellular immunotherapy in MM
Salomon Manier (Lille, France)
10:00 – Coffee break
10:20 – Group photo
Industrial Symposium III
Chair(s) : name(s) of chair(s) (city, country)
10:30 – Title
Name of presenter (city, country)
11:00 – Title
Name of presenter (city, country)
11:30 – 12:15
Keynote lecture: New insights into fine-tuning the actions of gc family cytokines
Chairs : Erwan Mortier (Nantes, France) & Suman Mitra (Lille, France)
Warren J. Leonard (Bethesda, USA)
12:15 – Lunch
Session SFGM-TC: CAR T-cell toxicity and patient’s management
Chairs : Stéphanie Nguyen (Paris), Raynier Devillier (Marseille)
13:10 – Stem cell transplantation as a backbone for modern cell- and gene therapy
Stephan Mielke (Stockholm, Sweden)
13:30 – Immune effector hematotoxicity : European Guidelines
Marion Subklewe (München, Germany)
13:50 – Place of Anakinra in ICANS
Jordan Gauthier (Seattle, USA) TBC
14:10 – Myeloid neoplasms following CAR T for lymphoid malignancies
Ibrahim Yakoub-Agha (Lille, France)
14:30 – Coffee break
Session CAR T beyond Leukemia and Lymphoma
Chairs: Geoffrey Guittard (Marseille, France) & Arnaud Scherpereel (Lille, France)
15:00 – B-cell Engineering
Michel Cogné (Rennes, France)
15:20 – CAR monocytes for cancer immunotherapy
Jean-Luc Perfettini (city, France)
15:40 – Personalized T-cell therapies for solid cancers
Alena Gros (city, Spain)
16:00 – Coffee break
Modulating the Tumor Microenvironment
Chairs : Christelle Harly (Nantes, France) & Emmanuel Donnadieu (Paris, France)
16:00 – Stemness and Maintenance of Treg lineage.
Rahul Roychoudhuri (Cambridge, UK) TB
16:50 – Lymphoma Microenvironment
Karin Tarte (Rennes, France)
17:10 – Metabolic barriers to cancer immunotherapy
Greg Delgoffe (Pittsburg, USA)
17:40 – ion channels in T-cell immunotherapy
Robert Eil (Oregon, USA)
18:00 – Closing remarks
20:00 – Gala dinner
Friday September 8th, 2023
08:30 – Welcome and registration
Session GRAALL & SFCE :
Chairs: Nicolas Boissel (Paris, France) & André Baruchel (Paris, France)
9:00 – New CAR T-cell development in T-ALL
Paul Maciocia (London, UK) TBC
9:20 – B-ALL: Are two targets better than one?
Ching-Hon Pui (Memphis, USA) TBC
9:40 – Title
Name of presenter (city, country)
Round table : point-of-care production
Chairs : Ibrahim Yakoub-Agha (Lille, France), Christian Chabannon (Marseille, France)
10:00 – Centralized production versus point-of-care production
Chrystel Marton (Lille, France)
10:10 – Difficulties and challenge for point-of-care production
Arnon Nagler (Tel Aviv, Israel)
0:20 – Academic vector production
Ulrike koehl (Liebzig, Germany)
10:30 – Round table
Olivier Boyer (Rouen, France), Jérôme Larghero (Paris, France), Camille Giverne (Rouen, France), Christophe Ferrand (Besançon, France), Arnon Nagler (Tel Aviv, Israel), Chrystel Marton (Lille, France).
11:00 – Coffee break
Symposium NOVARTIS
Chair(s): name(s) of chair(s) (city, country)
11:30 – Title
Name of presenter (city, country)
Academic session
Chairs: Louis Terriou (Lille, France) & Dominique Farge-Bancel (Paris, France)
12:00 – Incorporating radiation with Car T-cell therapy
Omran Saifi (Florida, USA)
12:20 – Boosting antitumoral T cell responses with the epichaperome inhibitor PU-H71 : perspectives for CAR T cell and other cellular immunotherapies
Monica Guzman (NY, USA)
12:40 – Infections and CAR T
David Beauvais (Lille, France)
13:00 – CAR-T cell therapy for Lupus
Georg Schett (city, Germany)
13:30 -Lunch break
SFI & CITC session : Harnessing immune signaling for innovative cell therapy
Chairs : Laurence Bataille (Paris, France) & Jacques Nunès (Marseille, France)
14:30 – Integrated approaches to dissect signaling in T cells
Romain Roncagalli (Marseille, France)
14:50 – Can we learn about CAR T cells by studying immune synapse formation ?
Claire Hivroz (Paris, France)
15:10 – Deciphering metabolic regulation in lymphocytes to improve future cell therapies
Antoine Marçais (Lyon, France)
15:30 – End of the meeting and conclusions
Suman Mitra & Ibrahim Yakoub-Agha